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Both influence mitochondrial function, inflammatory tone, and the molecular machinery that governs neuronal survival and repair, engaging the same PI3K-Akt signaling pathway established earlier, now operating within neurons rather than peripheral tissue

That opportunity is often missed

A smaller subset of patients report that semaglutides appetite suppression and the resulting reduction in food-seeking behavior actually makes their ADHD feel more apparent, not because symptoms worsen, but because food was serving as a stimulating activity that occupied the ADHD brain, and without it, the restlessness and distractibility become more noticeable

PMID: 43 PatrizioANewmanSKTuttleRMBoucaiL